Are Prescription Painkillers as Addictive as Heroin?

  1. Table of ContentsPrint
  2. The Link Between Painkillers and Heroin
  3. Can Pills Really Be as Addictive as Heroin?
  4. Pills to Heroin: A Terrifyingly Common Transition
  5. The Surge in Prescription Opioid Use and Abuse
  6. Getting Help for Opiate Addiction

Common Prescription Opioids

According to the National Institute on Drug Abuse (NIDA), in 2011, 4.2 million Americans aged 12 or over had used heroin at least once in their lives.  Of these users, an estimated 23% will go on to become heroin addicts, making heroin one of the most addictive drugs on the planet.

Recent years have witnessed an alarming surge in teenage heroin use and overdose, per the Centers for Disease Control (CDC). Scientists have attributed this rise to the rampant abuse of prescription painkillers. While only a very small percentage of those prescribed painkillers go on to abuse heroin, research studies have shown that nearly 50% of heroin users surveyed started with prescription painkillers.

One research study found that the odds of eventual heroin use were 3.5 times as likely for those who had (illicitly) abused prescription painkillers compared to those who hadn’t (Robertson, 2010). If you are suffering or you're worried about someone close to you, you are  not alone. Learn how to help a painkiller addict.




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Can Pills Really Be as Addictive as Heroin?

Why does abuse of painkillers lead to heroin use in so many cases? Are prescription painkillers just a pill-form of heroin? Are they just as addictive? Are their physical and psychological effects the same as heroin’s?

Prescription painkillers and heroin are indeed very similar.  While heroin is considered an opiate drug – that is, derived from opiate alkaloid substances extracted directly from the opium poppy – many prescription painkillers are technically opioids, which are opiates’ synthetic variants.  By this definition, even our own naturally occurring endorphin neuropeptides are opioids. Endorphins are synthesized by the human body, share molecular composition with botanically derived opiates and are utilized to achieve the same ends as prescription painkillers: pain management.  Both pharmaceutically manufactured and endogenous opioids interact with opioid receptors to elicit their effects.  There are innumerable opioid receptors scattered throughout different areas of the brain. Depending on which specific sub-population of receptors is stimulated, opioids can influence our perception of pain, activate our innate reward systems, and impact basic homeostatic processes like breathing and heart rate.

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While limited, our body's opioid reserves are able to relieve pain immediately following traumatic injury. These reserves, however, quickly run out, and severe pain sets in.  For these cases, along with milder injuries and other chronic pain-producing ailments, opioid painkillers may be prescribed.

The active opioid/opiate molecules in both painkillers and heroin attach themselves to opioid receptors in the brain. This provides pain relief and affects the brain’s reward pathways by triggering a large release of dopamine—ultimately resulting in a sense of intense well-being.

While these effects may feel stimulating, opioids are actually depressants.  In cases of opioid/heroin overdose, the systems responsible for breathing and heart rate may become significantly impaired, leading to:

  • Depressed respiration.
  • Coma.
  • Death.

The Heroin High vs. Opioid High

Heroin and painkiller infographic
Click the image above for the full infographic.

Prescription painkillers and heroin have similar physical and psychological effects. Someone high on heroin or painkillers will mostly likely feel:

  • Euphoria.
  • Decreased awareness of pain.
  • Drowsiness.
  • Confusion.
  • Nausea and vomiting.

The intensity of an opiate or opioid high is influenced not only by the drug dosage, but by the method of consumption:

  • Oral consumption (ingesting) generally results in slower-onset of effects, with weaker peak intensity. An average dose of a prescription painkiller, then, will not produce the same high as heroin.
  • Snorting or injecting opioids is relatively fast-acting, producing a more intense high, especially with higher dosages. Because heroin is most often injected and particularly potent, its effects are consistently powerful—one of many reasons why those addicted to painkillers move on to heroin. But painkillers, when snorted, injected, and/or consumed in high doses, can be equally powerful.

Heroin vs. Opioid Withdrawal

Whether addicted to heroin or prescription painkillers, abrupt cessation will produce intensely uncomfortable, flu-like withdrawal symptoms.  Most common are:Withdrawal symptoms in response to cessation of low dosage painkillers are most likely mild and tolerable.  However, as tolerance and addiction develop, the user will increase dosage and frequency of use and are consequently subject to much more intense withdrawal symptoms.

  • Nausea.
  • Fever.
  • Sweating.
  • Anxiety.
  • Muscle pain.
  • Abdominal cramps.
  • Diarrhea.
  • Nausea.
  • Vomiting.
  • Agitation.
  • Increased heart rate.

Withdrawal symptoms in response to cessation of low dosage painkillers are most likely mild and tolerable.  However, as tolerance and addiction develop, the user will increase dosage and frequency of use and are consequently subject to much more intense withdrawal symptoms.


Pills to Heroin: A Terrifyingly Common Transition

Many opioid painkillers and heroin share remarkably similar chemical structures and desirable effects, which may help to explain the startling connection between prescription opioid abuse and the subsequent initiation of heroin use.

The CDC estimates that someone addicted to opioid painkillers is 40 times more likely to abuse or develop an addiction to heroin than non-opioid users.

There are a few hypothesized reasons that painkiller addicts eventually transition to heroin abuse. For one, heroin may be easier to obtain than a prescription, Secondly, it’s relatively inexpensively priced on the illicit market. Currently, heroin is easy to get and cheaper than ever.  Prescription painkillers can be difficult to get ahold of in the first place, and prohibitively expensive once you do.

This trend in accessibility and pricing has become especially pronounced since 2013, when the Food and Drug Administration announced that they would be tightening controls on painkiller access by limiting the number of refills an individual could have before returning to the doctor for a new prescription. With these limitations in place, many turned to illegal methods in order to acquire opioid painkillers, which quickly become a gateway towards heroin abuse. One pill can cost up to $80 on the street, while one balloon of heroin can be as cheap as $10.

Because most painkiller addicts ingest or snort their product, those making the initial transition to heroin typically do so by way of smoking or snorting.  However, people that had already been injecting painkillers make the transition to injectable heroin with relative ease.


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The Surge in Prescription Opioid Use and Abuse

Research from SAMHSA revealed that an estimated 25 million people started nonmedical use of pain relievers between 2002 and 2011. In addition, a startling 16,651 deaths were attributed to prescription opioid medications in 2010 (Mack, 2013).

Although doctors attempt to screen patients for drug abuse or the propensity to develop substance dependency issues, millions of Americans continue to be prescribed opioid painkillers every year. The potential for abuse and addiction is dangerously high. Many people get addicted without realizing there’s a problem. They may be in denial of the potential dangers because of the notion that, as prescribed pharmaceuticals, the drugs are completely safe.

Some clinics in the United States have taken advantage of the overall popularity and demand for prescription painkillers.  Known as “pill mills”, these companies engage in various activities involving the illicit sale and distribution of prescription painkillers. The pill mill epidemic was particularly bad in Florida, where in 2011, there were 856 pain clinics. The astounding numbers of pill mills in Florida correlated with rising levels of prescription drug overdoses. In 2010 alone, Florida saw more than 1500 oxycodone-related overdoses, equating to more than four deaths each day.

In more recent years, law enforcement officials have been cracking down on these pill mills, while state and federal organizations continue to strategize methods to stem the epidemic of prescription opioid abuse.


Getting Help for Opiate Addiction

If you or someone you know is suffering under the weight of prescription pill abuse and/or heroin addiction, you are not alone. There are a number of treatment options available. Call 1-888-744-0069 to find a program.

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Due to the highly addictive nature of opioids and the intensity of their withdrawal symptoms (which sap the resolve of many making an attempt at recovery), the Substance Abuse and Mental Health Services Administration  (SAMHSA) has made recommendations for an approach to recovery known as Medically-Assisted Treatment (MAT). Patients who receive MAT complete a supervised detox program that includes a tapering regimen of opioid medication, and tapering refers to a process of gradually reducing the dosage and frequency with which a substance is used. The goal is to manage serious withdrawal symptoms and wean the body completely off the substance. Upon completion of detox, various behavioral therapy interventions will usually begin as the core of addiction treatment.

Behavioral therapies include:

  1. Supportive therapy – Offers general emotional support to the patient.
  2. Cognitive-behavioral therapy - Targets specific thoughts and behaviors that led to and maintained drug use. Also used to prevent relapse by identifying triggers and modifying behavioral reactions to them.
  3. Group therapy – Involves interacting with other opioid addicts who serve as a support group throughout the treatment process
  4. Family therapy - Involves family in therapy to discuss family dynamics that contributed to the start or maintenance of drug use.

Individuals can receive these services on an inpatient or outpatient basis.  Inpatient treatment takes place at a hospital or residential treatment center.  While both offer 24-hour care and will arrange for medical assistance, when needed, a residential center provides more of a home-like feel.  Residential centers are more likely to have exercise rooms, lounges and other amenities.  One major benefit to any form of inpatient treatment is that the risk of relapse is minimized throughout your stay.

Outpatient therapy includes similar access to substance abuse counseling and therapy, as well as any needed medical care, but the patient leaves the clinic or treatment center at the conclusion of each day’s session to sleep and/or attend work or other obligations.  Individuals who have relatively mild addictions, those who feel they cannot afford to take a leave of absence from work, or those reluctant to postpone their school or family responsibilities might choose outpatient treatment.

It’s always a wise decision to undergo evaluation from a knowledgeable addiction treatment specialist, who may then make an educated recommendation for the level of treatment that you would likely benefit from the most. Many with tenacious opioid dependencies find that inpatient treatment provides an immersive environment, free from toxic triggers or distractions and ultimately provides them the best chance for a successful recovery.

The treatment durations of various inpatient care programs will vary and may depend on both your level of addiction as well as the specific services provided by the center.  When choosing the right inpatient care, you might want to consider the following:

  1. Proximity to your home – If friends and family are supportive of your treatment, and pose no risk of relapse, choosing a center close to home might be the best option. Other individuals – those whose family, friends or homes could pose a threat to successful treatment – might consider seeking addiction treatment further away from home.
  2. Cost – Many insurance companies will provide at least partial coverage for inpatient or outpatient substance abuse treatment. Check with your treatment provider and insurance company to see how much, if any, you will need to pay out of pocket.
  3. Services provided – Most importantly, ensure that your residential center can and will attend to all of your needs. For example, if you concurrently struggle with some form of mental illness in addition to an opioid addiction, look for a center that offers specialized dual diagnosis treatment. You may also have a preference for additional holistic therapies – like yoga, a focus on nutrition, meditation, etc. – that are offered only through select programs.

There are a multitude of options for those looking to find treatment for addiction. If you need help determining what’s best for you or how to find the type of care you want, simply call 1-888-744-0069.  Our treatment admissions specialists are available to help you 24 hours a day.


Sources:

  • National Institute on Drug Abuse. (2014, October). Drug Facts: Heroin. Retrieved February 8, 2016, from http://www.drugabuse.gov/publications/drugfacts/heroin
  • Center for Disease Control. (2015, July 7). Today's Heroin Epidemic. Retrieved February 8, 2016, from http://www.cdc.gov/vitalsigns/heroin/
  • National Institute on Drug Abuse. (2014, November). Prescription Drug Abuse: What are Opioids? Retrieved February 8, 2016, from http://www.drugabuse.gov/publications/research-reports/prescription-drugs/opioids/what-are-opioids
  • National Institute on Drug Abuse. (2015, December). Prescription Opioids and Heroin: Heroin Use is Driven by its Low Cost and High Availability. Retrieved February 9, 2016, from https://www.drugabuse.gov/publications/research-reports/relationship-between-prescription-drug-abuse-heroin-use/heroin-use-driven-by-its-low-cost-high-availability
  • Medline Plus. (2013, April 5). Opiate Withdrawal. Retrieved February 8, 2016, from https://www.nlm.nih.gov/medlineplus/ency/article/000949.htm
  • Rigg, K. K., & Monnat, S. M. (2015). Comparing Characteristics of Prescription Painkiller Misusers and Heroin Users in the United States. Addictive behaviors, 51, 106-112.
  • Substance Abuse and Mental Health Services Administration. (2016, January 7). Medication-Assisted Treatment. Retrieved February 9, 2016, from http://www.samhsa.gov/medication-assisted-treatment
  • Daniulaityte, R., Falck, R., & Carlson, R. G. (2012). “I’m not afraid of those ones just ‘cause they’ve been prescribed”: Perceptions of risk among illicit users of pharmaceutical opioids. International journal of drug policy, 23(5), 374-384.
  • Mars, S. G., Bourgois, P., Karandinos, G., Montero, F., & Ciccarone, D. (2014). “Every ‘never’I ever said came true”: Transitions from opioid pills to heroin injecting. International Journal of Drug Policy, 25(2), 257-266.
  • Robertson, C. J. (2015). The Association of Lifetime Nonmedical Use of Prescription Pain Killers and Heroin Use (Doctoral dissertation, San Diego State University).
  • Dart, R. C., Surratt, H. L., Cicero, T. J., Parrino, M. W., Severtson, S. G., Bucher-Bartelson, B., & Green, J. L. (2015). Trends in opioid analgesic abuse and mortality in the United States. New England Journal of Medicine, 372(3), 241-248.
  • Results from the 2011 National Survey on Drug Use and Health: summary of national findings. (NSDUH series H-44, HHS publication no. (SMA) 12-4713.) Rockville, MD: Substance Abuse and Mental Health Services Administration, 2012.
  • National Vital Statistics System. Multiple cause of death file. Atlanta: Centers for Disease Control and Prevention, 2012 (http://www.cdc.gov/nchs/data/dvs/Record _Layout_2012.pdf).
  • National Institute on Drug Abuse. (2014, November). How do Opioids Affect the Brain and Body? Retrieved February 9, 2016, from http://www.drugabuse.gov/publications/research-reports/prescription-drugs/opioids/how-do-opioids-affect-brain-body
  • Muhuri, P., Gfroerer, J., & Davies, M. (2013, August 1). Associations of Nonmedical Pain Reliever Use and Initiation of Heroin Use in the United States. Retrieved November 11, 2015, from http://archive.samhsa.gov/data/2k13/DataReview/DR006/nonmedical-pain-reliever-use-2013.htm
  • Meier, B. (2013, October 24). F.D.A. Urging a Tighter Rein on Painkillers. The New York Times. Retrieved November 11, 2015, from http://www.nytimes.com/2013/10/25/business/fda-seeks-tighter-control-on-prescriptions-for-class-of-painkillers.html
  • America's Addiction to Opioids: Heroin and Prescription Drug Abuse. (2014, May 14). Retrieved November 11, 2015, from http://www.drugabuse.gov/about-nida/legislative-activities/testimony-to-congress/2015/americas-addiction-to-opioids-heroin-prescription-drug-abuse
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