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Facts About Krokodil (The “Zombie Drug”)

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What Is Krokodil?

Desomorphine (dihydrodesoxymorphine) or Krokodil, is an injectable opioid derivative of codeine. On the street and online, the drug is known as:

  • Krokodil.
  • Crocodile.
  • Croc.
  • Krok.
  • Russian Magic.
  • Poor Man’s Heroin.

The name “krokodil” is thought to either derive from the appearance of a user’s skin around the injection site (which may become discolored and scaly—resembling that of a crocodile) or be in reference to chlorocodide (a codeine derivative and chemical precursor used in desomorphine production).

Krokodil is a Schedule I substance in the United States, meaning it has high abuse potential and no accepted medicinal use.

Desomorphine: A Cheap Substitute for Heroin

Krokodil use has spread rapidly across Russia, with at least 100,000 people having injected the drug in 2011. Krokodil was reportedly first used in Russia in 2003 (Gahr et. al., 2012), and it continues to spread to surrounding countries like the Ukraine, Georgia, and Kazakhstan. Although use is concentrated in the Soviet region, countries like Germany and Norway have also reported cases of krokodil use.

Krokodil is made from codeine and codeine-containing medications. In some drug markets where heroin is relatively difficult to obtain, people have turned to alternatives such as krokodil as a heroin substitute.


Krokodil Drug Effects

Krokodil is attractive to those seeking a euphoric high because it is cheap, relatively easy to make or obtain, produces a high similar to that of heroin, and delivers potent sedative and pain-relieving effects in the user. Krokodil’s effects have a very fast onset of about 2-3 minutes and last for approximately 2 hours.

The drug, while cheap, produces a relatively short high, and various media sources have covered stories about addicted individuals who need to frequently administer krokodil to maintain their high and avoid withdrawal symptoms.


Krokodil Manufacturing

Users are said to be able to make krokodil in roughly 45 minutes with codeine and minimal equipment. Users attempting to create desomorphine often do so by combining several toxic ingredients like hydrochloric acid, household cleaners, and gasoline with codeine. They may also sometimes add cigarette ash to balance the pH.

A lingering question among researchers is whether or not krokodil cooks actually produce desomorphine due to “bootleg” manufacturing processes (Grund et al., 2013).


Krokodil Side Effects and Dangers of Use

Krokodil’s side effects can be extremely serious. Injection of the drug can cause:

When the drug is injected, it can damage veins and lead to localized infections. These infections may ultimately spread to other areas and cause organ damage. If parts of the body—such as the limbs—are badly infected, doctors may need to amputate or perform surgery on an individual.

Because krokodil is a homemade opioid, the conditions in which it is prepared can introduce a number of potential health risks. Users making the drug often share preparation equipment and syringes for injection. The sharing of needles increases the risk for HIV and hepatitis C virus (HCV) transmission among individuals. Because krokodil is a drug administered frequently throughout the day, this can significantly increase the likelihood of unsafe, non-sterile needle use.

Even short-term use of krokodil can lead to severe health complications and death. Fatalities among chronic users are common within 2-3 years of the first dose, but even the first use can be fatal in some instances (Skowronek, Celiski, Chowaniec, 2012).


Why Is Krokodil Called a “Zombie Drug”?

scary and blurry image of group of men

Krokodil has been called a “zombie drug” by the media. Most reports of krokodil use in the media have shown addicted individuals who have gangrene or eschars (dead patches of skin) on their bodies.

The skin of krokodil injection users can become black, grey, green, and scabby and can flake off—resembling the skin of a reptile or crocodile at the site of injection.

There have been numerous sensational reports about the appearance of krokodil in the United States based on a small number of suspected cases. However, the National Institute on Drug Abuse (NIDA) had not confirmed any cases of krokodil use in the country as of 2013.

Find Krokodil Addiction Treatment Programs

If you or a loved one is struggling with a substance use problem, help is available and recovery is possible. Rehab programs are located throughout the U.S. and offer a variety of treatment types. You can use SAMHSA’s Find Treatment tool to search for facilities or visit your state government website to acquire local drug and alcohol resources by doing a web search for your state name and ‘.gov.’

American Addiction Centers (AAC) is a leading treatment provider and has trusted rehab programs across the country. To speak with a caring AAC representative, please contact us free at .

Krokodil Addiction Treatment Levels of Care

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