Get help today 888-744-0069 or sign up for 24/7 text support.
American Addiction Centers National Rehabs Directory

Effects of Spice Use: Short-Term, Long-Term, Side Effects, and Treatment

Is Spice Harmful?

“Spice” (synthetic marijuana) has grown in popularity in recent years. Synthetic marijuana is sold under a variety of names other than “Spice,” including:

  • K2.
  • Skunk.
  • Moon rocks.
  • Potpourri.

Substances like Spice and K2—which contain smokable plant material coated with synthetic cannabinoids or other substances—are often sold in gas stations and head shops. Because Spice can be purchased legally in many places, and because it is often advertised as a “natural” marijuana alternative, many use it under the guise of safety. Being easily obtainable, and with a public perception as an innocuous natural high, Spice and K2 carry much appeal for teens and younger adults.

Synthetic marijuana, however, is not natural and can have a number of dangerous side effects. It can also be addictive and it can produce severe withdrawal symptoms in those who discontinue use.

Many countries, states, and other localities have made synthetic marijuana illegal due to its side effects. Today, most leading government and industry health organizations officially view synthetic cannabinoids as dangerous and addictive drugs.

A Spice/K2 user is much more likely to experience serious adverse effects than a person smoking natural cannabis. These adverse effects may include psychotic symptoms such as paranoia and hallucinations. Furthermore, Spice use has been implicated in cases of kidney failure and heart attacks. With reported effects including reduced blood flow to the heart (myocardial ischemia), abuse of these substances can lead to severe and lasting heart conditions.

Short-Term Effects of Spice Use

Synthetic marijuana or “Spice” is often sought for the following effects, which mimic those of natural marijuana:

  • Euphoric feelings.
  • Altered perception.
  • Feelings of relaxation.

These desirable feelings, however, are often countered by dangerous side effects, which vary by the specific chemical compounds present in the drug (which are unregulated, and frequently changing) and may include:

  • Increased heart rate.
  • Hypertension.
  • Myocardial ischemia.
  • Vomiting.
  • Hallucinations.
  • Paranoia.
  • Severe anxiety.
  • Panic attacks.
  • Aggression.

Long-Term Effects of Spice Use

The long-term effects of Spice use are largely unknown due to the drug’s status as a relatively new drug on the market. However, heart damage from myocardial ischemia and renal damage are severe effects that have been reported. Both, obviously, are ominous signs of the potential long-term consequences of abusing this drug.

Frequent Spice use has also been known to elicit seizure activity in some individuals.

Spice Dependence

Unlike marijuana, synthetic cannabinoids like Spice and K2 frequently elicit withdrawal symptoms—some quite severe. Withdrawing from Spice can be extremely uncomfortable, with symptoms including:

  • Headache.
  • Diaphoresis (sweating).
  • Tremors.
  • Drug cravings.
  • Psychotic symptoms, such as paranoia and hallucinations.
  • Mood changes/depression.
  • Suicidal ideation.

Finding Treatment for Spice Addiction

One of the telltale signs that a physical drug addiction has developed is the presence of an associated withdrawal syndrome. When long-term Spice users attempt to quit, serious withdrawal symptoms can occur—as mentioned above.

Management of withdrawal can sometimes involves a formal detoxing period—in the case of Spice, this can often take a week or longer.

Substance abuse treatment will commence after detox is completed, and it can last anywhere from 1-6 months or longer, depending on a number of factors—including the severity of the drug dependency and any complicating social issues. Many drug treatment programs require the patient to stay in the rehab for the duration of treatment—these are known as inpatient programs—while other programs are implemented on an outpatient basis.

Time and/or budget constraints are a serious concern for many, and they sometimes necessitate a shorter residential stay or outpatient treatment.

The severity of a person’s illness will naturally play a part in deciding the nature of the program they embark on. It is always a good idea to undergo formal evaluation of your specific substance abuse situation and any related issues by an addiction treatment professional, who will then help make a recommendation for the type of treatment that will be most beneficial.

Residential programs provide the patient with full-time care that includes round-the clock medical treatment, support, and guidance. These programs often last 30 days90 days (or longer, depending upon the seriousness of the patient’s condition).

Private/Luxury Rehab Programs

Luxury rehab centers are available at a higher price point and include a range of amenities, such as:

  • Acupuncture.
  • Spa treatments.
  • Aromatherapy.
  • Equine therapy.
  • Golf courses.

Executive Rehab Programs

Executive rehab facilities are specifically targeted to those who can’t leave their businesses during treatment.

These facilities allow computer access and mobile devices so that patients can continue working while receiving care.

Holistic Rehab Programs

Holistic programs help patients by enhancing the mind-body-spirit connection while they undergo treatment.

Exercises such as yoga, meditation, and other Eastern practices are conducted to help manage stress, minimize distractions, and allow those in treatment to focus on their most important goal, which is recovery from addiction.

What Happens After Treatment Ends?

As a formal treatment period approaches its end, most comprehensive treatment programs will have already made thorough aftercare preparations to ensure continuity of care as you progress through your recovery. Some of these aftercare options include:

  • Weekly check-ins. Weekly check-ins by phone are conducted to monitor the progress of patients and help with any obstacles.
  • Drop-in sessions. These sessions allow patients to stop by the center for meetings whenever they need additional support.
  • Support Programs. Support programs can consist of group therapy, support groups, family therapy, etc.

Deciding upon the right type of rehab for you starts with first knowing what is out there and then having a discussion with a medical professional you trust.

Call American Addiction Centers (AAC) free at to learn more about treatment and how to find your way back from addiction.

Was this page helpful?
Thank you for your feedback.

American Addiction Centers (AAC) is committed to delivering original, truthful, accurate, unbiased, and medically current information. We strive to create content that is clear, concise, and easy to understand.

Read our full editorial policy

While we are unable to respond to your feedback directly, we'll use this information to improve our online help.