Many substances of abuse can lead to the development of physiological dependence—especially if they are taken in large amounts and for a long period of time. When a person becomes dependent on a substance and then decides to stop using it, they may be at risk of experiencing unpleasant addiction withdrawal symptoms.1
People who have recently stopped taking their drug of choice may experience both physical withdrawal symptoms and mental side effects. Withdrawals can be better navigated with the right help. If you or a loved one is struggling with substance use and wants to get help, it’s important to understand how drug and alcohol withdrawal symptoms can affect you. This page will help you learn more about:
- Common withdrawal symptoms of drug and alcohol abuse.
- Causes of drug and alcohol withdrawal.
- Treatment for withdrawal symptoms.
- Medication-assisted treatment (MAT).21
- Effectiveness of treatment for alcohol and drug addiction.
What is Drug or Alcohol Withdrawal?
You may be wondering, ‘what is withdrawal in addiction?’ or ‘what are withdrawal symptoms?’ Drug or alcohol withdrawal involves the physical, mental and behavioral changes that can occur after suddenly cutting back on or stopping the prolonged use of substances.1, 2, 3 The effects of withdrawal from drugs are multifarious. The character and severity of withdrawal can vary in association with different substances, but symptoms may be quite pronounced when people are attempting to quit alcohol and other substances such as opioids, benzodiazepines and sedatives.3
Substances like opioids, alcohol and sedatives can carry significant risks when going through withdrawal. These can range from mild to potentially dangerous and severe withdrawal symptoms. Medical detox – as opposed to detoxing from home – can be a safe way to help manage the withdrawal symptoms of drugs under the care of treatment professionals.3, 4
Causes of Alcohol and Drug Withdrawal
The human body strives to be in a state of balance, known as homeostasis, and actively works to restore any imbalances that arise.5 Drinking and using drugs can greatly alter certain types of brain activity to disrupt normal homeostasis. Over time, when you use a substance regularly, your brain may make its own adjustments (i.e. neuroadaptations) to counter the chemical changes brought about by that specific substance.6
However, once you cut back or stop using, your brain may temporarily struggle to reach homeostasis again. It is this period of adjustment, which may involve a rebalancing of a number of chemical messengers known as neurotransmitters, that is thought to lead to withdrawal symptoms for several types of substances.5, 6
In other terms, these neuroadaptations resulting from continued drug or alcohol use lead to the development of physiological dependence. Dependent individuals grow so accustomed to the presence of a substance that they essentially rely on its continued use to feel and function normally.6, 7, 8 People with substance dependence are likely to experience some degree of the side effects of withdrawal when attempts are made to slow or altogether stop their substance use.
Types of Withdrawal Symptoms
Drug and alcohol withdrawal symptoms can range from mild to severe, depending on the substance being used.1, 3, 4 They also depend on how long and how heavily you’ve been using.1, 5 The withdrawal symptoms of drug abuse and alcohol addiction can be difficult to deal with and may lead people back to using their substance of choice in an effort to alleviate the discomfort.3
You can experience withdrawal symptoms for various types of substances, from marijuana and alcohol to stimulants such as cocaine and concerta, sedatives such as valium/diazepam, opioids such as subutex and heroin (also known as dope sickness).3 Significantly severe signs of withdrawal are associated with substances such as alcohol, benzodiazepines such as librium and opioids. Stimulants and marijuana are other substances that are associated with potentially uncomfortable withdrawal syndromes, though symptoms are often relatively less pronounced than those experienced during opioid, alcohol and benzodiazepine withdrawal.3 The following sections give more detail about substance-specific types of withdrawal symptoms.
Withdrawal symptoms of alcohol addiction can start between 6 to 24 hours after heavy, prolonged drinking is stopped. Symptoms can progressively worsen over the next 2-3 days, then will slowly improve until they are resolved by about the 10th day.3, 4 Some typical symptoms of alcohol withdrawal include:3, 4
- Rapid heart rate.
- Increased blood pressure.
- Nausea or vomiting.
- Hand tremors.
Acute alcohol withdrawal can be dangerous and potentially life-threatening.4 Severe symptoms can include agitation, seizures and delirium tremens, which involves difficulty regulating body temperature and blood pressure, sweating, hallucinations and confusion.3, 4, 5, 10 Some of the symptoms of withdrawal for people suffering from alcoholism can be dangerous and could require immediate medical attention.4 Medical detoxification and withdrawal management can help keep people as safe and comfortable during the difficult drug and alcohol detox period of early recovery.
Benzodiazepines are central nervous system depressants commonly prescribed to manage anxiety, panic disorder and certain seizure disorders.4, 8 Some examples of benzodiazepines include: 3, 4, 8, 11
Mixing benzodiazepines with opioids or other CNS depressants such as alcohol can lead to dangerous levels of sedation and respiratory depression, increasing the side effects and the risk of a fatal overdose.8, 11, 12
Though the time of onset may vary, withdrawal symptoms following prolonged benzodiazepine abuse can appear within hours to days after stopping relatively short-acting benzodiazepines such as Ativan, or within several days to a week after you stop taking longer-acting benzodiazepines such as Valium.3
Longer-acting benzos can have protracted withdrawal effects. Shorter-acting benzodiazepine withdrawal symptoms might take a few days to peak in intensity, with many symptoms then resolving within 4-5 days. Longer-acting benzos might lead to withdrawal symptoms that peak in the 2nd week and largely resolve by the 3rd or 4th week, though lower-intensity symptoms may linger in some individuals for several months and take up to 8 weeks to resolve.3 Potential symptoms of benzodiazepine withdrawal include:3, 4, 6
- Difficulty concentrating or remembering.
- Achy or tense muscles.
- Rapid pulse.
- Increased sensitivity to light, smells and sounds.
- Rapid pulse.
Opioid addiction is commonly associated with opioid withdrawal symptoms when use is stopped.3 While symptoms of opiate withdrawal aren’t typically life-threatening, there may be some dangerous complications. For example, aspirating vomit into the lungs can lead to infection, and ongoing vomiting and diarrhea can cause dehydration and electrolyte imbalances.4, 13 Symptoms of opioid withdrawal include:3, 4, 5, 6, 13
- Dilated pupils.
- Excessive yawning.
- Runny nose.
- Watery eyes.
- Sweating and fever.
- Increased pain sensitivity.
- Achy muscles and joints.
- Nausea or vomiting.
Stimulant abuse often occurs in patterns of heavy use (known as binges) followed by crashes, where use is stopped and withdrawal symptoms arise.3 Illicit central nervous system stimulants include crystal methamphetamine, cocaine and crack. Some prescription stimulant medications such as methylphenidate (Ritalin) and dextroamphetamine (Adderall) are also subject to abuse.3, 4, 14
Stimulant withdrawal symptoms are typically not dangerous. Though rare, serious depression with suicidal thoughts or behaviors can be present during detox and should be monitored closely.6, 14 Symptoms of stimulant withdrawal can include:3, 4, 6, 14
- Depression or dysphoria.
- Increased appetite.
- Changes in sleep patterns—either excessive sleep or insomnia.
- Moving faster or slower than usual.
- Aching muscles.
- Strong cravings for the substance.
Marijuana comes from dried parts of the Cannabis plant containing tetrahydrocannabinol (THC) and other psychoactive compounds.15 If you suddenly stop long-term, heavy use, even if it is medical marijuana, it’s possible you may experience signs of drug withdrawal for as long as 1 to 2 weeks. Common withdrawal symptoms of marijuana include:3, 4, 6, 16, 17, 18
- Depressed mood.
- Cravings for marijuana.
- Upsetting dreams.
- Loss of appetite.
- Abdominal pain.
- Tremors or shakiness.
Post-Acute Withdrawal Syndrome or PAWS
You may be wondering, ‘what is Post-Acute Withdrawal?’ While withdrawal symptoms are uncomfortable, typically, they end after 2 weeks, especially with the help of a medically managed detox. Some drugs, however, can lead to a protracted withdrawal process, lasting for many months or even a year. People who consume a heavy amount of an intoxicating substance over a long period of time are more likely to develop this condition, known as Post-Acute Withdrawal Syndrome or PAWS. PAWS refers to symptoms that persist after acute withdrawal symptoms have resolved. PAWS symptoms, which rarely involve physical withdrawal symptoms, can be just as intense as those experienced during acute withdrawal. People may experience irritability, anxiety, depression, mood swings, low energy, insomnia, lack of focus and a lack of libido. Post Acute Withdrawal symptoms can put a person at risk of relapse, since they may return to drug use in order to put an end to the discomfort.
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Rehab Treatment for Drug and Alcohol Withdrawal Symptoms
You may be wondering how to manage alcohol and drug withdrawal symptoms. Professional detoxification and withdrawal management can provide medical and mental health care for people who are going through symptoms of withdrawal from drugs and alcohol.4, 19 Medical and psychiatric support and monitoring are available so that any physical and mental health symptoms can be addressed as needed.4, 9, 19 In some cases, medications may be used to ease symptoms of drug withdrawal and prevent complications from arising during medically managed withdrawal.9
Withdrawal symptoms, potential risks and available treatments vary by substance, so the type of withdrawal management you receive will differ accordingly.9 If you are planning to cut back or stop using a substance, you should consult with your doctor or a treatment professional to discuss the risks and determine the safest and most effective form of withdrawal management for you.
What is a Detox Program?
Detoxification programs primarily focus on getting you through the withdrawal process safely and comfortably. Though an important step, detox often does little to address the underlying psychological, behavioral and social issues that contribute to addiction.2 Detox is only the first stage in the recovery process and should be followed up with additional forms of treatment in order to be most effective.2, 4
Types of Drug and Alcohol Addiction Treatment
Continuing addiction treatment after withdrawal management, or detox, is an important step toward long-term recovery.9, 13 As you get close to completing detox, your treatment team will discuss a longer-term treatment plan that best suits your needs and will help facilitate your entry into additional treatment, whether it be in the same location as the detox program or elsewhere.
In follow-up treatment programs, you can learn coping skills and relapse prevention techniques, improve your communication skills and receive medication treatment, if needed.9
Treatment that may include substance withdrawal can occur in a variety of settings, depending on your needs and the intensity of your substance withdrawal symptoms.2, 8 There is a continuum of treatment settings where detox and rehab services are available including:2, 22
- Outpatient treatment: A person can live at home and continue working while receiving treatment. This typically involves less than 9 weekly hours of treatment.
- Intensive outpatient: A person can live at home and continue working while receiving treatment for complex needs such as co-occurring mental health conditions. This type of treatment typically involves 9 or more weekly hours of treatment.
- Partial hospitalization: A person can live at home and continue working while receiving treatment for multidimensional instabilities. This typically involves at least 20 weekly hours of outpatient treatment.
- Residential treatment: A person lives at the treatment facility to receive 24-hour support from medical, mental health and addiction treatment professionals. This typically involves a minimum of 5 weekly hours of clinical care.
- Medically managed inpatient drug and alcohol treatment: A person receives 24-hour nursing care and daily care from a physician to address severe and/or unstable problems. This level of care involves 24/7 medical monitoring, plus the availability of counseling staff for up to 16 hours a week.
As you move through drug and alcohol recovery, your treatment plan may need to be reevaluated and adjusted to meet your needs, as they may change.9 Additionally, longer periods of any form of addiction treatment (3 months or more) may be most helpful in reducing drug or alcohol use and improving treatment outcomes.9
Dealing with substance abuse and withdrawal is difficult and can be overwhelming. You may have questions about drug and alcohol withdrawal and treatment and American Addiction Centers is here to help. Our compassionate admissions navigators are available 24/7 to help you understand treatment options, including where you can receive withdrawal management for the unpleasant symptoms of coming off substances. You can also learn how to pay for rehab and how to access treatment without insurance. Call us for free at to learn more. You can also verify your benefits.
Substance-Specific Support Information